Drusilla was the youngest daughter of Herod Agrippa I by his wife Cypros. Drusilla became the wife of Felix, the governor of Judea. Drusilla was with Felix when Paul spoke of his faith to the procurator.
According to the historian, Josephus, Drusilla was a Jewess who married Azizus, king of Emesa, who then converted to Judaism. Because of her great beauty, Felix desired her for his wife. Drusilla then left Azizus and married the Gentile Felix in defiance of Jewish law.